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40. 40. Preac-Mursic V, Pfister HW, Spiegel H, Burk R, Wilske B, Reinhardt S, Bohmer R. PreAc Mursic-V, Pfister HW, Spiegel H, Burk R, Wilske B, Reinhardt S, Bohmer R. First isolation of Borrelia burgdorferi First isolation of Borrelia burgdorferi

from an iris biopsy. from an iris biopsy. J. J. Clin. Clin. Neuroophthalmol. Neuroophthalmol. 1993 Sep;13(3):155-61. September 1993, 13 (3) :155-61.

41. 41. Oksi J, Viljanen MK, Kalimo H, Peltonen R, Marttia R, Salomaa P, Nikoskelainen J, Budka H, Halonen P. Oksi J, Viljanen MK, Kalimo H, Peltonen R, R Marttia, Salomaa P, Nikoskelainen J, Budka H, Halonen P. Fatal Fatal

encephalitis caused by concomitant infection with tick-borne encephalitis virus and Borrelia burgdorferi . encephalitis Caused by concomitant infection with tick-borne encephalitis virus and Borrelia burgdorferi. Clin Infect Clin Infect

Dis. Say. 1993 Mar;16(3):392-6. March 1993, 16 (3) :392-6.

42. 42. Skripnikova IA, Anan'eva LP, Barskova VG, Ushakova MA. Skripnikova IA, Anan'eva LP VG Barskova, Ushakova MA. [The humoral immunological response of patients with [The humoral immunological response of patients with

Lyme disease.]Ter Arkh 1995;67(11):53-6. Lyme disease.] Ter Arkh 1995; 67 (11) :53-6.

43. 43. Klempner MS, Schmid CH, Hu L, Steere AC, Johnson G, McCloud B, Noring R, Weinstein A. Klempner MS, Schmid CH, Hu L, Steere AC, Johnson G, B McCloud, Noring R, Weinstein A. Intralaboratory Intralaboratory

reliability of serologic and urine testing for Lyme disease.Am J Med. reliability of serologic and urine testing for Lyme disease.Am J Med. 2001 Feb 15;110(3):217-9. 2001 Feb 15, 110 (3) :217-9.

44. 44. Banyas GT. Banyas GT. Difficulties with Lyme serology. Difficulties with Lyme serology. J Am Optom Assoc. J Am Optom Assoc. 1992 Feb;63(2):135-9. 1992 Feb; 63 (2) :135-9.

45. 45. Faller J, Thompson F, Hamilton W. Faller J, Thompson F, Hamilton W. Foot and ankle disorders resulting from Lyme disease. Foot and ankle disorders resulting and from Lyme disease. Foot Ankle. Foot Ankle. 1991 1,991

Feb;11(4):236-8. Feb; 11 (4) :236-8.

46. 46. Nields JA, Kueton JF.Tullio phenomenon and seronegative Lyme borreliosis. Nields JA, Kueton JF.Tullio phenomenon and seronegative Lyme borreliosis. Lancet. Lancet. 1991 Jul 13;338(8759):128-9. 1991 Jul 13, 338 (8759) :128-9.

47. 47. Schutzer SE, Coyle PK, Belman AL, Golightly MG, Drulle J. Schutzer SE, Coyle PK, Belman AL, Golightly MG, J. Drulle Sequestration of antibody to Borrelia burgdorferi in Sequestration of antibody to Borrelia burgdorferi in

immune complexes in seronegative Lyme disease. immune complexes in seronegative Lyme disease. Lancet. Lancet. 1990 Feb 10;335(8685):312-5. 1990 Feb 10, 335 (8685) :312-5.

48. 48. Paul A. Paul A. [Arthritis, headache, facial paralysis. [Arthritis, headache, facial paralysis. Despite negative laboratory tests Borrelia can still be the cause]. DESPITE negative laboratory tests Borrelia can still be the cause]. MMW MMW

Fortschr. Fortschr. Med 2001 Feb 8;143(6):17. Med 2001 Feb 8; 143 (6): 17.

49. 49. Ang CW, Notermans DW, Hommes M, Simoons-Smit AM, Herremans T. Ang CW, Notermans DW, Men's M, Simoons-Smit AM, Herremans T. Large differences between test strategies Large differences Between test strategies

for the detection of anti- Borrelia antibodies are revealed by comparing eight ELISAs and five immunoblots. for the detection of anti-Borrelia antibodies are Revealed by Comparing eight ELISAs and five immunoblots. Eur J Eur J

Clin Microbiol Infect Dis. Clin Microbiol Infect Dis. Published oline: 27 Jan 2011 Oline Published: January 27, 2011

50. 50. Wojciechowska-Koszko et al.: Serodiagnosis of borreliosis: indirect immunofluorescence assay, enzyme-linked Wojciechowska-Koszko et al.: Serodiagnosis of borreliosis: indirect immunofluorescence assay, enzyme-linked

immunosorbent assay and immunoblotting. immunosorbent assay and immunoblotting. Arch Immunol Ther Exp (Warsz.) 2011 Feb;59(1):69-77. Arch Immunol Ther Exp (Warsz.) 2011 Feb; 59 (1) :69-77. Epub 2011 Jan Epub 2011 Jan

22. 22.

51. 51. Durovska J. Durovska J. et al.: Our experience with examination of antibodies against antigens of Borrelia burgdorferi in patients et al.: Our experience with antibodies against antigens of examination of Borrelia burgdorferi in patients

with suspected lyme disease. with Suspected Lyme disease. Bratisl Lek Listy. Lek Listy Bratisl. 2010;111(3):153-5. 2010, 111 (3) :153-5.

Sources scientifiques prouvant la non-fiabilité de la sérologie (référence française) : Scientific sources proving the unreliability of serology (French reference):

52. 52. Surveillance de la maladie de Lyme - Département de l'Ain, de la Loire et de la Haute-Savoie, Bulletin d'information Monitoring Lyme disease - Department of Ain, Loire and Haute-Savoie Newsletter

n°4 - Période de surveillance du 1er avril 2006 au 31 mars 2008. # 4 - Monitoring period 1 April 2006 to 31 March 2008.

→Une sérologie a été prescrite pour 247 cas présentant un érythème migrant : 40 % des sérologies étaient → serology was prescribed for 247 cases with erythema migrans: 40% serologies were

négatives ou douteuses. negative or doubtful.

Sources scientifiques prouvant la non-fiabilité de la PCR par ponction lombaire : Scientific sources proving the unreliability of PCR by lumbar puncture:

53. 53. Coyle PK, Schutzer SE, Deng Z, Krupp LB, Belman AL, Benach JL, Luft BJ. Coyle PK, Schutzer SE, Deng Z, Krupp LB, Belman AL, Benach JL, Luft BJ. Detection of Borrelia burgdorferi-specific Detection of Borrelia burgdorferi-specific

antigen in antibody-negative cerebrospinal fluid in neurologic Lyme disease. antigen in antibody-negative cerebrospinal fluid in neurologic Lyme disease. Neurology. Neurology. 1995 Nov;45(11):2010-5. November 1995, 45 (11) :2010-5.

54. 54. Steere AC, Berardi VP, Weeks KE, Logigian EL, Ackermann R. Steere AC, Berardi VP, Weeks KE, Logigian EL, Ackermann R. Evaluation of the intrathecal antibody response to Evaluation of the intrathecal antibody response to

Borrelia burgdorferi as a diagnostic test for Lyme neuroborreliosis. Borrelia burgdorferi as a diagnostic test for Lyme neuroborreliosis. J Infect Dis 1990 Jun;161(6):1203-9. J Infect Dis 1990 Jun; 161 (6) :1203-9.

55. 55. Logigian EL, Kaplan RF, Steere AC. Logigian EL, Kaplan RF, Steere AC. Successful treatment of Lyme encephalopathy with intravenous ceftriaxone. Successful treatment of Lyme encephalopathy with intravenous ceftriaxone. J J

Infect Dis 1999;180:377–83. Infect Dis 1999; 180:377-83.

56. 56. Logigian EL, Kaplan RF, Steere AC. Logigian EL, Kaplan RF, Steere AC. Chronic neurologic manifestations of Lyme disease. Chronic neurologic manifestations of Lyme disease. N Engl J Med N Engl J Med

1990;323:1438–44. 1990, 323:1438-44.

57. 57. Pfister HW, Preac-Mursic V, Wilske B, Einhaupl KM, Weinberger K. Pfister HW, PreAc Mursic-V, Wilske B, Einhaupl KM, Weinberger K. Latent Lyme neuroborreliosis: presence of Lyme neuroborreliosis latent: presence of